UJI AKTIVITAS EKSTRAK ETANOL DAUN MATOA (Pometia pinnata J.R & G.Fors) TERHADAP BAKTERI PENYEBAB INFEKSI SALURAN PENCERNAAN

Hakim, Azalia Azizah Wardhani and Herwin, Herwin and Fitriana, Fitriana (2024) UJI AKTIVITAS EKSTRAK ETANOL DAUN MATOA (Pometia pinnata J.R & G.Fors) TERHADAP BAKTERI PENYEBAB INFEKSI SALURAN PENCERNAAN. Other thesis, Universitas Muslim Indonesia.

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Abstract

AZALIA AZIZAH WARDHANI HAKIM, Antibacterial Activity of Ethanol
Extract of Matoa Leaves (Pometia Pinnata J.R & G.Fors.) against Bacteria
Causing Gastrointestinal Infections (Supervised by Herwin and Fitriana)
Matoa leaves (Pometia pinnata J.R & G.Fors.) empirically can treat
various diseases such as hypertension, diarrhea, dysentery and contain
flavonoids, tannins and saponins which function as antibacterials. This study
aimed to examine the antibacterial assay of the ethanol extract of Pometia
pinnata J.R & G.Fors leaves on bacteria causing gastrointestinal infections
using agar diffusion. Then, it continued on antibacterial screening using
concentrations of 0.1% and 0.5%, Minimum Inhibitory Concentration testing
(MIC), and Minimum Bactericidal Concentration (MBC) testing using different
concentrations of 0.0125%, 0.025%, 0.05%, 0.1%, 0.2%, 0.4%, 0.8%, 1.6%
on E. coli, V. cholerae and S. dysenteriae bacteria. The results from the
screening test at 0.1% concentration showed activity against E. coli and S.
dysentriae while V. cholerae and S. typhi did not indicate any reaction.
Further, a concentration of 0.5% reported activity against E. coli, S.
dysentriae and V. cholerae bacteria, but S. typhi bacteria did not prove
reaction. The MIC test results obtained values at 0.0125% in E. coli, V.
cholerae, and S. Dysentriae and MBC value at the concentration found 0.2%
in E. coli, V. cholerae and S. dysentriae. Meanwhile, the results of the
antibacterial assay of the ethanol extract of Matoa leaves confirmed the
largest diameter of the inhibition zone at a concentration of 1.6% and 11.36
mm in V. cholerae bacteria. Based on these results, it can be concluded that
the ethanol extract of matoa leaves contains antibacterial activity against
bacteria causing gastrointestinal infections such as E. coli, V. cholerae, and
S. dysentriae.
Keywords : Antibacterial, Matoa Leaves (Pometia pinnata J.R & G.Fors.),
and Gastrointestinal infection

Item Type:	Thesis (Other)
Subjects:	R Medicine > R Medicine (General) R Medicine > RS Pharmacy and materia medica
Divisions:	FAKULTAS FARMASI
Depositing User:	operator 10
Date Deposited:	10 Oct 2024 03:26
Last Modified:	10 Oct 2024 03:26
URI:	http://192.168.168.84/id/eprint/7009

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